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Intensive Care Medicine

, Volume 41, Issue 9, pp 1517–1528

First Online: 21 July 2015


Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications.

KeywordsBrain chemistry Microdialysis Outcome Subarachnoid hemorrhage Traumatic brain injury The participants of the 2014 International Microdialysis Forum are listed in the electronic supplementary material 134 2015 3930 MOESM1 ESM.

Electronic supplementary materialThe online version of this article doi:10.1007-s00134-015-3930-y contains supplementary material, which is available to authorized users.

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