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Critical Care

, 19:307

First Online: 01 September 2015


Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain e.g., intracerebral hemorrhage, a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.

AbbreviationsCBFCerebral blood flow

HBOTHyperbaric oxygen therapy

ICHIntracerebral hemorrhage

paO2Arterial partial pressure of oxygen

PbTO2Brain tissue oxygenation

pO2Oxygen partial pressure

See related research by Zhu et al., http:-www.ccforum.com-content-19-1-255-abstract

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Author: Amir Hadanny - Shai Efrati

Source: https://link.springer.com/

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