A Prospective Study of Platelet-Rich Plasma as Biological Augmentation for Acute Achilles Tendon Rupture RepairReportar como inadecuado

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BioMed Research International - Volume 2016 2016, Article ID 9364170, 8 pages -

Clinical Study

Shanghai Jiaotong University Affiliated Sixth People’s Hospital, Shanghai 200233, China

The People’s Hospital of Shigatse City, Shigatse, Tibet 857000, China

Received 1 July 2016; Revised 26 November 2016; Accepted 7 December 2016

Academic Editor: Hong-Yun Li

Copyright © 2016 Jian Zou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Acute Achilles tendon rupture is one of the most common tendon injuries in adults. We hypothesized that Platelet-Rich Plasma PRP can be used as biological augmentation for surgical treatment of acute Achilles tendon rupture. Our study is a prospective randomized controlled trial. Patients with acute Achilles tendon rupture undergoing surgical repair were randomly assigned into either control group or PRP group. End-to-end modified Krackow suture was performed in both groups. In the PRP group, PRP was injected into the paratenon sheath and around the ruptured tissue after the tendon was repaired. Postoperatively we evaluated isokinetic muscle strength at 3, 6, 12, and 24 months. In addition, ankle ROM, calf circumference, Leppilahti score, and the SF-36 score were evaluated at 6, 12, and 24 months after operation. At 3 months, the PRP group had better isokinetic muscle. The PRP group also achieved higher SF-36 and Leppilahti scores at 6 and 12 months. At 24 months, the PRP group had an improved ankle range of motion compared to the control group. Our study results suggest that PRP can serve as a biological augmentation to acute Achilles tendon rupture repair and improves both short and midterm functional outcomes.

Autor: Jian Zou, Xiaolian Mo, Zhongmin Shi, Tanzhu Li, Jianfeng Xue, Guohua Mei, and Xiaolin Li

Fuente: https://www.hindawi.com/


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