A commentary on the 2015 Canadian Clinical Practice Guidelines in glutamine supplementation to parenteral nutritionReportar como inadecuado




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Critical Care

, 20:7

First Online: 08 January 2016

Abstract

Glutamine is one of the conditionally essential free amino acids with multiple biological functions. Its supplementation to parenteral nutrition has been widely used for the management of complications in intensive care. However, controversial clinical reports have generated reluctance in the use of this pharmaco-nutrient. In this commentary, we address the impact of four studies that influenced the recommendations on glutamine supplementation by the Canadian Clinical Practice Guide 2015. Because of the importance of this guideline in clinical practice, we strongly believe that a more rigorous and critical evaluation is required to support recommendations in future guidelines.

AbbreviationsAAamino acid

ENenteral nutrition

GHgrowth hormone

Glnglutamine

i.v.intravenous

ICUintensive care unit

IGFinsulin-like growth factor

LOSlength of stay

REDOXReducing Deaths due to Oxidative Stress

TPNtotal parenteral nutrition

An erratum to this article can be found at http:-dx.doi.org-10.1186-s13054-016-1203-y.

An erratum to this article is available at http:-dx.doi.org-10.1186-s13054-016-1203-y.

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Autor: Alberto Leguina-Ruzzi

Fuente: https://link.springer.com/







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