Total Hip Arthroplasty in Systemic Lupus Erythematosus: A Systematic ReviewReport as inadecuate

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International Journal of Rheumatology - Volume 2015 2015, Article ID 475489, 8 pages -

Review Article

Department of Trauma and Orthopaedics, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK

University of Glasgow, Glasgow G12 8QQ, UK

University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthpaedic Hospital, Stanmore HA7 4LP, UK

Received 23 August 2014; Accepted 14 November 2014

Academic Editor: Umile Giuseppe Longo

Copyright © 2015 John W. Kennedy and Wasim Khan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The prognosis of systemic lupus erythematosus SLE has greatly improved in recent years, resulting in an increased number of patients reporting musculoskeletal complications such as osteonecrosis of the femoral head. Total hip arthroplasty THA can be utilised to alleviate the pain associated with this; however postoperative outcomes in patients with SLE are uncertain. A systematic review of the literature was conducted to identify articles presenting results of THA in SLE, and nine suitable papers were found. All papers were level IV evidence. Pooling the results, a total of 162 patients underwent 214 total hip arthroplasties. Mean follow-up was 72.5 months. The mean Harris Hip Score improved from 45.5 preoperatively to 88.6 and last follow-up. Seventeen percent of patients experienced at least one complication. Superficial wound infection occurred in 3.3%. Revision was required in 2.8% of cases. The mortality rate was 18.5% however no deaths were attributable to undergoing THA. Given the paucity of data present in the literature, more studies are required to adequately assess the postoperative outcomes of THA in patients with SLE, particularly complication rates.

Author: John W. Kennedy and Wasim Khan



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