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Journal of Thyroid Research - Volume 2016 2016, Article ID 8470252, 3 pages -

Research Article

Department of Pathology, Faculty of Medicine, Gaziantep University, 27310 Gaziantep, Turkey

Department of Otorhinolaryngology, Faculty of Medicine, Gaziantep University, 27310 Gaziantep, Turkey

Received 27 October 2015; Revised 22 February 2016; Accepted 5 April 2016

Academic Editor: Gary L. Francis

Copyright © 2016 Suna Erkilic et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Tumor multifocality and bilaterality of papillary thyroid carcinoma PTC are important factors when selecting the most appropriate surgical procedure. The aim of this study was to assess the bilaterality rate in PTC and the relationship between the tumor size and bilaterality. Materials and Methods. Thyroidectomy specimens with a diagnosis of PTC were retrospectively reviewed in the Pathology Department of a tertiary care medical center. Specimens were divided into three groups according to the size of the primary and contralateral tumor foci. Tumors less than or equal to 1 cm in each lobe were included in group 1. Group 2 consisted of tumors greater than 1 cm in one lobe and less than 1 cm in the other lobe. Tumors greater than 1 cm in each lobe were included in group 3. Results. We identified 868 total thyroidectomy specimens with a diagnosis of PTC between 2001 and 2011. Of these cases, both thyroid lobes were involved in 262 cases 32%. There were 109 42%, 121 46%, and 32 cases 12% in group 1, group 2, and group 3, respectively. Conclusion. Bilaterality is frequent in PTC and is not related to tumor size. Accordingly, the high frequency of bilateral disease in PTC should be kept in mind when determining the extent of the surgical procedure.





Autor: Suna Erkilic, Fatih Celenk, and Zehra Bozdag

Fuente: https://www.hindawi.com/



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