Efficacy of Contact Needle Therapy for Chemotherapy-Induced Peripheral NeuropathyReport as inadecuate

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Evidence-Based Complementary and Alternative MedicineVolume 2013 2013, Article ID 928129, 5 pages

Research Article

Department of Otorhinolaryngology and Head and Neck Surgery, Clinic of Japanese Oriental Kampo Medicine, Kanazawa University Hospital, 13-1 Takaramachi, Kanazawa-City, Ishikawa 920-8641, Japan

Department of Anesthesiology, Kanazawa Medical University Hospital, 1-1, Daigaku, Uchinada, Kahoku-gun, Ishikawa 920-0265, Japan

Department of Surgery, Japanese Red Cross Kanazawa Hospital, Mima 2-251, Kanazawa 921-8162, Japan

Mukeido Acupuncture and Moxibustion Office, Niku 126-7, Horikawa, Koizumi-cho, Toyama 939-8081, Japan

Received 28 March 2013; Accepted 29 April 2013

Academic Editor: Yoshiharu Motoo

Copyright © 2013 Keiko Ogawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cancer chemotherapy-induced peripheral neuropathy CIPN often results in discontinuation of treatment with potentially useful anticancer drugs and may deteriorate the patient’s quality of life. This study investigated the effect of contact needle therapy CNT on CIPN caused by responsible chemotherapeutic agents as taxanes and oxaliplatin. Six patients with CIPN were treated with CNT. The severity of CIPN was evaluated using the Common Terminology Criteria for Adverse Events CTCAE version 4 and FACT-GOG-Ntx before and after CNT. After the treatment, all of the patients showed some improvement. Four patients showed apparent improvement in breakthrough pain. One of the cases had difficulty in walking because of CIPN in lower extremities, but after 2 times of CNT, he could walk without pain and could continue the chemotherapy. Although its putative mechanisms remain elusive, CNT has strong potential as an adjunctive therapy in CIPN. Well-designed clinical trials with adequate sample size and power are necessary to confirm the findings of this study.

Author: Keiko Ogawa, Masao Ogawa, Koji Nishijima, Masaki Tsuda, and Genichi Nishimura

Source: https://www.hindawi.com/


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