En-Face- Spectral-Domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot SyndromeReport as inadecuate

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Journal of OphthalmologyVolume 2014 2014, Article ID 928028, 6 pages

Clinical Study

Department of Ophthalmology, Croix-Rousse University Hospital, Hospices Civils de Lyon, University of Medicine Lyon 1, 103 Grande rue de la Croix Rousse, 69317 Lyon Cedex 04, France

Professor Sahel Department, Rothschild Ophthalmologic Foundation, 25 rue Manin, 75019 Paris, France

Kleber Retinal Center, 50 Cours Franklin Roosevelt, 69006 Lyon, France

Monticelli Paradis Retinal Center, 88 rue du Commandant Rolland, 13008 Marseille, France

Received 12 August 2013; Revised 17 February 2014; Accepted 19 February 2014; Published 22 April 2014

Academic Editor: Hermann Mucke

Copyright © 2014 Flore De bats et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. The recent use of -en-face- enhanced-depth imaging spectral-domain optical coherence tomography EDI SD-OCT helps distinguish the retinal layers involved in the physiopathology of multiple evanescent white dot syndrome MEWDS. Methods. Four patients presenting with MEWDS underwent a comprehensive ocular examination including C-scan -en-face- EDI SD-OCT at the initial visit and during follow-up. Results. C-scans combined with the other multimodal imaging enabled the visualization of retinal damage. Acute lesions appeared as diffuse and focal disruptions occurring in the ellipsoid and interdigitation zones. The match between autofluorescence imaging, indocyanine green angiography, and -en-face- OCT helped identify the acute microstructural damages in the outer retina further than the choroid. Follow-up using -en-face- EDI-OCT revealed progressive and complete recovery of the central outer retinal layers. Conclusion. -En-face- EDI SD-OCT identified the site of initial damage in MEWDS as the photoreceptors and the interdigitation layers rather than the choroid. Moreover -en-face- OCT is helpful in the follow-up of these lesions by being able to show the recovery of the outer retinal layers.

Author: Flore De bats, Benjamin Wolff, Vivien Vasseur, Aude Affortit, Laurent Kodjikian, José-Alain Sahel, and Martine Mauget-faÿs

Source: https://www.hindawi.com/


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