Large-scale study of long non-coding RNA functions based on structure and expression featuresReport as inadecuate




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Science China Life Sciences

, Volume 56, Issue 10, pp 953–959

First Online: 05 October 2013Received: 14 August 2013Accepted: 02 September 2013DOI: 10.1007-s11427-013-4556-3

Cite this article as: Zhao, Y., Wang, J., Chen, X. et al. Sci. China Life Sci. 2013 56: 953. doi:10.1007-s11427-013-4556-3

Abstract

Mammals and other complex organisms can transcribe an abundance of long non-coding RNAs lncRNAs that fulfill a wide variety of regulatory roles in many biological processes. These roles, including as scaffolds and as guides for protein-coding genes, mainly depend on the structure and expression level of lncRNAs. In this review, we focus on the current methods for analyzing lncRNA structure and expression, which is basic but necessary information for in-depth, large-scale analysis of lncRNA functions.

Keywordsnon-coding RNA structure expression function Contributed equally to this work

This article is published with open access at Springerlink.com

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Author: Yi Zhao - Jian Wang - XiaoWei Chen - HaiTao Luo - YunJie Zhao - Yi Xiao - RenSheng Chen

Source: https://link.springer.com/







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