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BMC Genomics

, 14:S6

First Online: 01 October 2013DOI: 10.1186-1471-2164-14-S4-S6

Cite this article as: Zhao, J., Huang, J.X. & Hu, X. BMC Genomics 2013 14Suppl 4: S6. doi:10.1186-1471-2164-14-S4-S6


In this paper, we propose an Advanced Bayesian-based Personalized Laboratory Tests recommendation BPLT model. Given a patient, we estimate whether a new laboratory test should belong to a -taken- or -not-taken- class. We use the bayesian method to build a weighting function for a laboratory test and the given patient. A higher weight represents that the laboratory test has a higher probability of being -taken- by the patient and lower probability of being -not-taken- by the patient. For the sake of effectiveness and robustness, we further integrate several modified smoothing techniques into the model. In order to evaluate BPLT model objectively, we propose a framework where the data set is randomly split into a training set, a validation input set and a validation label set. A training matrix is generated from the training data set. Then instead of accessing the training data set repeatedly, we utilize this training matrix to predict the laboratory test on the validation input set. Finally, the recommended ranking list is compared with the validation label set using our proposed metric CorrectRateM. We conduct experiments on real medical data, and the experimental results show the effectiveness of the proposed BPLT model.

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Author: Jiashu Zhao - Jimmy Xiangji Huang - Xiaohua Hu

Source: https://link.springer.com/

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