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Science China Life Sciences

, Volume 56, Issue 10, pp 891–896

First Online: 05 October 2013Received: 09 September 2013Accepted: 16 September 2013DOI: 10.1007-s11427-013-4558-1

Cite this article as: Qi, W., Song, X. & Li, L. Sci. China Life Sci. 2013 56: 891. doi:10.1007-s11427-013-4558-1


It is clear that RNA is more than just a messenger between gene and protein. The mammalian genome is pervasively transcribed, giving rise to tens of thousands of non-coding transcripts. Whether all of these transcripts are functional remains to be elucidated, but it is evident that there are many functional long non-coding RNAs lncRNAs. Recent studies have set out to decode the regulatory role and functional diversity of lncRNAs. Here we organize these studies to highlight the significant involvements of lncRNAs in regulation of gene expression and human physiological and pathological processes, which are achieved by their interaction with DNA, RNA or protein.

KeywordslncRNAs gene expression physiological and pathological processes interaction This article is published with open access at Springerlink.com

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Author: WenChuan Qi - Xu Song - Ling Li

Source: https://link.springer.com/

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