Moving RNA moves RNA forwardReport as inadecuate

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Science China Life Sciences

, Volume 56, Issue 10, pp 914–920

First Online: 05 September 2013Received: 23 July 2013Accepted: 23 August 2013DOI: 10.1007-s11427-013-4545-6

Cite this article as: Peng, L., Li, Y., Zhang, L. et al. Sci. China Life Sci. 2013 56: 914. doi:10.1007-s11427-013-4545-6


Cell communication affects all aspects of cell structure and behavior, such as cell proliferation, differentiation, division, and coordination of various physiological functions. The moving RNA in plants and mammalian cells indicates that nucleic acid could be one of the various types of messengers for cell communication. The microvesicle is a critical pathway that mediates RNA moving and keeps moving RNA stable in body fluids. When moving miRNA enters the target cell, it functions by altering the gene expression profile and significantly inhibiting mRNA translation in recipient cells. Thus, moving RNA may act as a long-range modulator during development, organogenesis, and tumor metastasis.

Keywordscell communication moving RNA microvesicle This article is published with open access at

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Author: LiNa Peng - YuJiao Li - Lan Zhang - WenQiang Yu


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