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Case Reports in Oncological Medicine - Volume 2017 2017, Article ID 6195898, 5 pages - https:-doi.org-10.1155-2017-6195898

Case Report

Department of Radiology, Nagasaki Harbor Medical Center City Hospital, Nagasaki, Japan

Department of Clinical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Department of Pathology, Nagasaki Harbor Medical Center City Hospital, Nagasaki, Japan

Department of Internal Medicine, Nagasaki Harbor Medical Center City Hospital, Nagasaki, Japan

Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Correspondence should be addressed to Kazuto Ashizawa

Received 24 January 2017; Revised 1 May 2017; Accepted 9 May 2017; Published 29 May 2017

Academic Editor: Jeanine M. Buchanich

Copyright © 2017 Reiko Ideguchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We herein report two cases of malignant pleural mesothelioma with marked lymphangiosis. The patients included a 68-year-old man and a 67-year-old man who both had a history of exposure to asbestos. Computed tomography CT on admission showed pleural effusion with pleural thickening. In both cases, a histopathological examination of the pleura confirmed the diagnosis of epithelioid malignant mesothelioma. They received chemotherapy, but the treatment was only palliative. The chest CT assessments during admission revealed marked pleural effusion and mediastinal lymphadenopathy. CT also showed a consolidative mass with bronchovascular bundle and septal thickening in the lungs suggesting pulmonary parenchymal involvement and the lymphangitic spread of the tumor. These CT findings mimicked lung cancer with pleuritis and lymphangitic carcinomatosis. Autopsy was performed in both cases. Macroscopically, the tumor cells infiltrated the lung with the marked lymphatic spread of the tumor. Microscopy also revealed that the tumor had invaded the pulmonary parenchyma with the marked lymphatic spread of the tumor. Although this growth pattern is unusual, malignant pleural mesothelioma should be considered as the differential diagnosis, especially in patients with pleural lesions.





Autor: Reiko Ideguchi, Kazuto Ashizawa, Saori Akashi, Michiko Shindo, Kazunori Minami, Toshio Fukuda, Junji Irie, Minoru Fukuda, 

Fuente: https://www.hindawi.com/



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