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Science China Life Sciences

, Volume 57, Issue 8, pp 795–801

First Online: 08 August 2014Received: 29 April 2014Accepted: 19 June 2014DOI: 10.1007-s11427-014-4699-x

Cite this article as: Lv, BJ., Li, J. & Cheng, X. Sci. China Life Sci. 2014 57: 795. doi:10.1007-s11427-014-4699-x

Abstract

Aortic aneurysms are common and life threatening problems with high rates of death. The initiation and progression of aneurysms are characterized by extensive extracellular matrix degradation and immune cells invasion within arterial wall. During the pathogenesis of all aneurysms, inflammation and immune cells play a significant role. Although T cells are abundant in aneurysm tissue, their functions in initiation and propagation of aneurysms remain unclear. This review summarizes the current state of knowledge of T lymphocytes on this disease and focuses on potential mechanisms of specific T cell responses.

KeywordsT cells cytokines aortic aneurysms inflammation pathogenesis This article is published with open access at link.springer.com

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Autor: Bing-Jie Lv - JingYong Li - Xiang Cheng

Fuente: https://link.springer.com/







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