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Science China Life Sciences

, Volume 57, Issue 10, pp 1034–1038

First Online: 26 April 2014Received: 06 February 2013Accepted: 10 September 2013DOI: 10.1007-s11427-014-4651-0

Cite this article as: Yu, D., Xiang, H., Li, D. et al. Sci. China Life Sci. 2014 57: 1034. doi:10.1007-s11427-014-4651-0


In previous research, time-delay Δt was a more important parameter than the reflection coefficient in the individual transfer function of central aortic pressure reconstruction. The Δt can be obtained by electrocardiography ECG or phonocardiography PCG. Because the pre-ejection period remains an uncertain factor, the present study used ECG and PCG to define the delay time and analyzed the accuracy of the reconstruction results. The Δtpre is the actual delay time derived from the aorta to the carotid pressure wave, ΔtPCG is the time delay between the aortic valve component of the second heart sound and the dicrotic incisura of the carotid pressure wave, and ΔtECG represents the delay from the interval of the ECG R-peak to the foot of the carotid pressure wave. Compared with the measured aortic pressure, the reconstruction result obtained by Δt=ΔtPCG slightly differed from the best result estimated by Δt=Δtpre. However, the differences between the result obtained by Δt=ΔtECG and the best result were significant in terms of the diastolic blood pressure, and pulse pressure, and especially in terms of the augmentation index and root-mean-square-error. Thus, the Δt should be determined by PCG for central aortic pressure reconstruction in practice.

Keywordscentral aortic pressure delay time PCG ECG This article is published with open access at

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Autor: DanYang Yu - HaiYang Xiang - DeYu Li - YuQi Wang - MengSun Yu


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