The plant Polycomb repressive complex 1 PRC1 existed in the ancestor of seed plants and has a complex duplication historyReportar como inadecuado




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BMC Evolutionary Biology

, 15:44

First Online: 13 March 2015Received: 16 December 2014Accepted: 24 February 2015DOI: 10.1186-s12862-015-0319-z

Cite this article as: Berke, L. & Snel, B. BMC Evol Biol 2015 15: 44. doi:10.1186-s12862-015-0319-z

Abstract

BackgroundPolycomb repressive complex 1 PRC1 is an essential protein complex for plant development. It catalyzes ubiquitination of histone H2A that is an important part of the transcription repression machinery. Absence of PRC1 subunits in Arabidopsis thaliana plants causes severe developmental defects. Many aspects of the plant PRC1 are elusive, including its origin and phylogenetic distribution.

ResultsWe established the evolutionary history of the plant PRC1 subunits LHP1, Ring1a-b, Bmi1a-c, EMF1, and VRN1, enabled by sensitive phylogenetic methods and newly sequenced plant genomes from previously unsampled taxonomic groups.

We showed that all PRC1 core subunits exist in gymnosperms, earlier than previously thought, and that VRN1 is a recent addition, found exclusively in eudicots. The retention of individual subunits in chlorophytes, mosses, lycophytes and monilophytes indicates that they can moonlight as part of other complexes or processes. Moreover, we showed that most PRC1 subunits underwent a complex, duplication-rich history that differs significantly between Brassicaceae and other eudicots.

ConclusionsPRC1 existed in the last common ancestor of seed plants where it likely played an important regulatory role, aiding their radiation. The presence of LHP1, Ring1 and Bmi1 in mosses, lycophytes and monilophytes also suggests the presence of a primitive yet functional PRC1.

KeywordsLHP1 EMF1 Ring1a Ring1b Bmi1a Bmi1b Bmi1c VRN1 Paralogous replacement AbbreviationsPRC1Polycomb repressive complex 1

H2AubUbiquitination of histone H2A

LHP1LIKE HETEROCHROMATIN PROTEIN 1

EMF1EMBRYONIC FLOWER 1

VRN1VERNALIZATION 1

WGDWhole genome duplication

OGOrthologous group

NLSNuclear localization signal

LECALast eukaryotic common ancestor

Electronic supplementary materialThe online version of this article doi:10.1186-s12862-015-0319-z contains supplementary material, which is available to authorized users.

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Autor: Lidija Berke - Berend Snel

Fuente: https://link.springer.com/



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