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Radiation Oncology

, 11:123

First Online: 21 September 2016Received: 27 October 2015Accepted: 13 September 2016DOI: 10.1186-s13014-016-0702-y

Cite this article as: Guo, L., Wang, G., Feng, Y. et al. Radiat Oncol 2016 11: 123. doi:10.1186-s13014-016-0702-y

Abstract

Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging MRI can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume definition in radiotherapy of brain tumors, and it presents the opportunities and challenges in the integration of multimodal functional MRI into clinical practice. The results indicate that specialized and robust post-processing algorithms and tools are needed for the precise alignment of targets on the images, and comprehensive validations with more clinical data are important for the improvement of the correlation between histopathologic results and MRI parameter images.

KeywordsBrain tumors Diffusion Perfusion Radiotherapy Tumor volume definition  Download fulltext PDF



Autor: Lu Guo - Gang Wang - Yuanming Feng - Tonggang Yu - Yu Guo - Xu Bai - Zhaoxiang Ye

Fuente: https://link.springer.com/







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