Impact of metabolic comorbidity on the association between body mass index and health-related quality of life: a Scotland-wide cross-sectional study of 5,608 participantsReportar como inadecuado




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BMC Public Health

, 12:143

Health policies, systems and management in high-income countries

Abstract

BackgroundThe prevalence of obesity is rising in Scotland and globally. Overall, obesity is associated with increased morbidity, mortality and reduced health-related quality of life. Studies suggest that -healthy obesity- obesity without metabolic comorbidity may not be associated with morbidity or mortality. Its impact on health-related quality of life is unknown.

MethodsWe extracted data from the Scottish Health Survey on self-reported health-related quality of life, body mass index BMI, demographic information and comorbidity. SF-12 responses were converted into an overall health utility score. Linear regression analyses were used to explore the association between BMI and health utility, stratified by the presence or absence of metabolic comorbidity diabetes, hypertension, hypercholesterolemia or cardiovascular disease, and adjusted for potential confounders age, sex and deprivation quintile.

ResultsOf the 5,608 individuals, 3,744 66.8% were either overweight or obese and 921 16.4% had metabolic comorbidity. There was an inverted U-shaped relationship whereby health utility was highest among overweight individuals and fell with increasing BMI. There was a significant interaction with metabolic comorbidity p = 0.007. Individuals with metabolic comorbidty had lower utility scores and a steeper decline in utility with increasing BMI morbidly obese, adjusted coefficient: -0.064, 95% CI -0.115 -0.012, p = 0.015 for metabolic comorbidity versus -0.042, 95% CI -0.067 -0.018, p = 0.001 for no metabolic comorbidity.

ConclusionsThe adverse impact of obesity on health-related quality of life is greater among individuals with metabolic comorbidity. However, increased BMI is associated with reduced health-related quality of life even in the absence of metabolic comorbidity, casting doubt on the notion of -healthy obesity-.

KeywordsBody mass index Health-related quality of life Obesity Overweight SF-12 Utility AbbreviationsBMIbody mass index

CIconfidence interval

Nnumber.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2458-12-143 contains supplementary material, which is available to authorized users.

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Autor: Zia Ul-Haq - Daniel F Mackay - Elisabeth Fenwick - Jill P Pell

Fuente: https://link.springer.com/



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