Fistuloclysis Improves Liver Function and Nutritional Status in Patients with High-Output Upper Enteric FistulaReportar como inadecuado

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Gastroenterology Research and Practice - Volume 2014 2014, Article ID 941514, 10 pages -

Clinical StudyDepartment of Surgery, Jinling Hospital, Medical School of Nanjing University, 305 East Zhongshan Road, Nanjing 210002, China

Received 3 December 2013; Revised 14 January 2014; Accepted 18 January 2014; Published 26 February 2014

Academic Editor: Vikram Kate

Copyright © 2014 Yin Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. We aimed to determine the efficacy of fistuloclysis in patients with high-output upper enteric fistula EF. Methods. Patients were assigned into the fistuloclysis group , receiving fistuloclysis plus total enteral nutrition TEN and the control group , receiving TEN. Laboratory variables were measured during the four-week treatment. Results. At baseline, variables were similar between the two groups. Delta value was defined as the changes from baseline to day 28. Compared with the control group, the fistuloclysis group showed greater improvements in liver function Delta total bilirubin TB: in the fistuloclysis group versus in the control group, ; Delta direct bilirubin DB: versus , ; Delta alkaline phosphatase ALP: versus , ; nutritional status Delta total protein: versus , ; Delta albumin: versus , . In the fistuloclysis subgroups, biliary fistula patients had the maximum number of variables with the greatest improvements. Conclusions. Fistuloclysis improved hepatic and nutritional parameters in patients with high-output upper EF, particularly in biliary fistula patients.

Autor: Yin Wu, Jianan Ren, Gefei Wang, Bo Zhou, Chao Ding, Guosheng Gu, Jun Chen, Song Liu, and Jieshou Li



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