Combined myoepithelial carcinoma and myoepithelioma in soft tissue: a case report and review of the literatureReportar como inadecuado

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Journal of Medical Case Reports

, 8:317

First Online: 24 September 2014Received: 27 February 2014Accepted: 07 August 2014DOI: 10.1186-1752-1947-8-317

Cite this article as: Mahdi, Y., Zouaidia, F., Zouhair, A. et al. J Med Case Reports 2014 8: 317. doi:10.1186-1752-1947-8-317


IntroductionSoft tissue myoepithelial carcinoma and myoepithelioma are rare entities, part of myoepithelial tumors. They were incorporated into the World Health Organization classification of soft tissue tumors in 2002. Here we present an exceptional case of myoepithelial carcinoma and myoepithelioma association. To the best of our knowledge, such an association has never been reported in the literature.

Case presentationWe report a case of myoepithelial carcinoma combined with myoepithelioma occurring in the soft tissue of the right forearm of an 84-year-old Arabian man. We describe the clinical, radiological and pathological features dominated by histological polymorphism. We will also describe the proposed histological criteria of malignancy and the major role of immunohistochemistry in positive and differential diagnosis. We finally mention the therapeutic arsenal available.

ConclusionThrough this work, we report that myoepithelioma of soft tissue can progress to malignant myoepithelioma.

AbbreviationsEMAEpithelial membrane antigen

EMCExtraskeletal myxoid chondrosarcoma

GFAPGlial fibrillary acidic protein


MPNSTMalignant peripheral nerve sheath tumor

MRIMagnetic resonance imaging

STMMSoft tissue malignant myoepithelioma.

Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-8-317 contains supplementary material, which is available to authorized users.

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Autor: Youssef Mahdi - Fouad Zouaidia - Abdelilah Zouhair - Mohamed Azouz - Kaoutar Znati - Ahmed Jahid - Mohamed Saleh Berrada -


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