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Health Economics Review

, 4:26

First Online: 23 October 2014Received: 06 February 2014Accepted: 19 September 2014DOI: 10.1186-s13561-014-0026-2

Cite this article as: Tetteh, E.K. & Morris, S. Health Econ Rev 2014 4: 26. doi:10.1186-s13561-014-0026-2

Abstract

Biologic drugs, as with all other medical technologies, are subject to a number of regulatory, marketing, reimbursement financing and other demand-restricting hurdles applied by healthcare payers. One example is the routine use of cost-effectiveness analyses or health technology assessments to determine which medical technologies offer value-for-money. The manner in which these assessments are conducted suggests that, holding all else equal, the economic value of biologic drugs may be determined by how much is spent on administering these drugs or trade-offs between drug acquisition and administration costs. Yet, on the supply-side, it seems very little attention is given to how manufacturing and formulation choices affect healthcare delivery costs. This paper evaluates variations in the administration costs of biologic drugs, taking care to ensure consistent inclusion of all relevant cost resources. From this, it develops a regression-based algorithm with which manufacturers could possibly predict, during process development, how their manufacturing and formulation choices may impact on the healthcare delivery costs of their products.

KeywordsAdministration costs Biologics Economic evaluation Formulation Manufacturing Electronic supplementary materialThe online version of this article doi:10.1186-s13561-014-0026-2 contains supplementary material, which is available to authorized users.

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Autor: Ebenezer K Tetteh - Stephen Morris

Fuente: https://link.springer.com/







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