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Journal of Medical Case Reports

, 4:259

First Online: 10 August 2010Received: 20 January 2009Accepted: 10 August 2010DOI: 10.1186-1752-1947-4-259

Cite this article as: Checchi, L., Nucci, M.C., Gatti, A.M. et al. J Med Case Reports 2010 4: 259. doi:10.1186-1752-1947-4-259


IntroductionAlthough the causes of sarcoidosis are still unknown, past and current studies have provided evidence that this disease may be associated with occupational exposure to specific environmental agents. We describe a case of sarcoidosis in a dental surgeon with long exposure to inorganic dusts. To the best of our knowledge, this is the first report of this kind in the literature.

Case presentationAt the beginning of 2000, a 52-year-old Caucasian man, who worked as a dental surgeon, presented with shortness of breath during exercise, cough and retrosternal pain. After diagnosis of sarcoidosis, a scanning electronic microscopy with X-ray microanalysis of biopsy specimens was used in order to determine whether the disease could be traced to an occupational environmental agent. Results showed the presence of inorganic dust particles within sarcoidotic granulomas, and demonstrated that the material detected was identical to that found in a powder used by our patient for several years.

ConclusionsAlthough these results cannot be considered as definitive proof, they do however provide strong evidence that this disease may be associated with material used by dental surgeons.

Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-4-259 contains supplementary material, which is available to authorized users.

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Autor: Luigi Checchi - Maria C Nucci - Antonietta M Gatti - Daniele Mattia - Francesco S Violante


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