A matched case–control study of preterm birth in one hospital in Beijing, ChinaReport as inadecuate

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Reproductive Health

, 12:1

First Online: 05 January 2015Received: 28 April 2014Accepted: 15 December 2014DOI: 10.1186-1742-4755-12-1

Cite this article as: Huang, A., Jin, X., Liu, X. et al. Reprod Health 2015 12: 1. doi:10.1186-1742-4755-12-1


BackgroundPreterm birth is an unresolved global health issue. The etiologies of preterm birth are complex and multifactorial. To examine risk factors related to preterm birth, a matched case–control study was conducted in a hospital in Beijing, China where little data on preterm birth have been published in the scientific literature.

MethodsA 1:1 matched case–control study was conducted in 172 pairs of women with preterm birth case group and term delivery control group. Eligible subjects were interviewed in person by well-trained investigators using a questionnaire. Information on obstetric diagnosis and newborns were abstracted from inpatients’ medical records. Univariate and multivariate conditional logistic regression models were used to measure the associations between related factors and preterm birth.

ResultsUnivariate analysis showed that 6 of 12 factors were associated with preterm birth. Multivariate results showed that gestational hypertension OR = 7.76, low gestational weight gain OR = 3.02, frequent prenatal care OR = 0.16, balanced diet OR = 0.36, and high gestational weight gain OR = 0.41 were associated with preterm birth.

ConclusionThis study provides information on preterm birth in Beijing, China, and it also lends support to existing evidence about the role of maternal nutritional status, prenatal care and gestational hypertension as risk factors for preterm birth.

KeywordsPreterm birth Case–control study Risk factors  Download fulltext PDF

Author: AiQun Huang - Xi Jin - XiaoHong Liu - SuHong Gao

Source: https://link.springer.com/

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