A three-year longitudinal evaluation of the forearm bone density of users of etonogestrel- and levonorgestrel-releasing contraceptive implantsReportar como inadecuado




A three-year longitudinal evaluation of the forearm bone density of users of etonogestrel- and levonorgestrel-releasing contraceptive implants - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Reproductive Health

, 4:11

First Online: 12 November 2007Received: 04 September 2007Accepted: 12 November 2007DOI: 10.1186-1742-4755-4-11

Cite this article as: Monteiro-Dantas, C., Espejo-Arce, X., Lui-Filho, J.F. et al. Reprod Health 2007 4: 11. doi:10.1186-1742-4755-4-11

Abstract

BackgroundThe aim of this study was to evaluate bone mineral density BMD at baseline and at 18 and 36 months of use of etonogestrel ENG-and levonorgestrel LNG-releasing contraceptive implants. This is a continuation of a previous study in which BMD was evaluated at baseline and at 18 months of use.

MethodsA total of 111 women, 19–43 years of age, wererandomly allocated to use one of the two implants. At 36 months of follow-up, only 36 and 39 women were still using the ENG- and LNG-releasing implants, respectively. BMD was evaluated at the distal and at the ultra-distal radius of the non-dominant forearm using dual-energy X-ray absorptiometry.

ResultsThere was no difference in the BMD of users of either implant at 18 and at 36 months. BMD was significantly lower at 18 and at 36 months at the distal radius in both groups of users compared to pre-insertion values; however, no difference was found at the ultra-distal radius.

ConclusionWomen 19–43 years of age using either one of these two contraceptive implants for 36 months had lower BMD values at the distal radius compared to pre-insertion values; however, no difference was found at the ultra-distal radius.

AbbreviationsBMD Bone mineral density

BMI Body mass index

CV Coefficient of variation

DEXA Double X-ray absorptiometry

DMPA Depot medroxyprogesterone acetate

ENG Etonogestrel

LNG Levonorgestrel

UNDP United Nations Development Programme

UNFPA United Nations Fund for Population Affaires

UNICAMP Universidade Estadual de Campinas

SD Standard deviation

WHO World Health Organization

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Autor: Cecilia Monteiro-Dantas - Ximena Espejo-Arce - Jeffrey F Lui-Filho - Arlete M Fernandes - Ilza Monteiro - Luis Bahamondes

Fuente: https://link.springer.com/







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