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International Journal of Biomaterials - Volume 2015 2015, Article ID 485275, 9 pages -

Review Article

Department of Operative Dentistry, Fluminense Federal University, 28625-650 Nova Friburgo, RJ, Brazil

Prosthodontics Department, University of São Paulo, 05508-000 São Paulo, SP, Brazil

School of Chemistry, Rio de Janeiro Federal University, 21941-909 Rio de Janeiro, RJ, Brazil

Received 16 September 2014; Revised 23 December 2014; Accepted 23 December 2014

Academic Editor: Abdelwahab Omri

Copyright © 2015 Juliana Mattos Corrêa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Silver has been used in medicine for centuries because of its antimicrobial properties. More recently, silver nanoparticles have been synthesized and incorporated into several biomaterials, since their small size provides great antimicrobial effect, at low filler level. Hence, these nanoparticles have been applied in dentistry, in order to prevent or reduce biofilm formation over dental materials surfaces. This review aims to discuss the current progress in this field, highlighting aspects regarding silver nanoparticles incorporation, such as antimicrobial potential, mechanical properties, cytotoxicity, and long-term effectiveness. We also emphasize the need for more studies to determine the optimal concentration of silver nanoparticle and its release over time.

Author: Juliana Mattos Corrêa, Matsuyoshi Mori, Heloísa Lajas Sanches, Adriana Dibo da Cruz, Edgard Poiate Jr., and Isis Andréa Ve



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