Ethno-Specific Risk Factors for Adverse Pregnancy Outcomes: Findings from the Born in Bradford Cohort StudyReport as inadecuate

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Maternal and Child Health Journal

, Volume 20, Issue 7, pp 1394–1404

First Online: 16 March 2016DOI: 10.1007-s10995-016-1936-x

Cite this article as: Stacey, T., Prady, S., Haith-Cooper, M. et al. Matern Child Health J 2016 20: 1394. doi:10.1007-s10995-016-1936-x


Objectives Preterm birth PTB and small for gestational age SGA are major causes of perinatal mortality and morbidity. Previous studies indicated a range of risk factors associated with these poor outcomes, including maternal psychosocial and economic wellbeing. This paper will explore a range of psycho-social and economic factors in an ethnically diverse population. Methods The UK’s Born in Bradford cohort study recruited pregnant women attending a routine antenatal appointment at 26–28 weeks’ gestation at the Bradford Royal Infirmary 2007–2010. This analysis includes 9680 women with singleton live births who completed the baseline questionnaire. Data regarding maternal socio-demographic and mental health were recorded. Outcome data were collected prospectively, and analysed using multivariate regression models. The primary outcomes measured were: PTB <37 weeks’ gestation and SGA <10th customised centile. Results After adjustment for socio-demographic and medical factors, financial strain was associated with a 45 % increase in PTB OR 1.45: 95 % CI 1.06–1.98. Contrary to expectation, maternal distress in Pakistani women was negatively associated with SGA OR 0.65: CI 0.48–0.88. Obesity in White British women was protective for PTB OR 0.67: CI 0.45–0.98. Previously recognized risk factors, such as smoking in pregnancy and hypertension, were confirmed. Conclusions This study confirms known risk factors for PTB and SGA, along with a new variable of interest, financial strain. It also reveals a difference in the risk factors between ethnicities. In order to develop appropriate targeted preventative strategies to improve perinatal outcome in disadvantaged groups, a greater understanding of ethno-specific risk factors is required.

KeywordsSmall for gestational age Preterm birth Born in Bradford Depression Financial strain Ethnic differences  Download fulltext PDF

Author: Tomasina Stacey - Stephanie Prady - Melanie Haith-Cooper - Soo Downe - Nigel Simpson - Kate Pickett


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