Frailty predicts trajectories of quality of life over time among British community-dwelling older peopleReport as inadecuate

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Quality of Life Research

, Volume 25, Issue 7, pp 1743–1750

First Online: 09 January 2016Accepted: 12 December 2015DOI: 10.1007-s11136-015-1213-2

Cite this article as: Kojima, G., Iliffe, S., Morris, R.W. et al. Qual Life Res 2016 25: 1743. doi:10.1007-s11136-015-1213-2


PurposeTo investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people.

MethodsAmong 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index FI constructed from 40 deficits at baseline. QOL was measured using Older People’s Quality of Life Questionnaire OPQOL six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty.

ResultsAt baseline, mean age was 73.1 range 65–90 and 62.0 % were women. Mean FI was 0.17 range 0.00–0.66, and mean OPQOL was 130.80 range 93–163. The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI regression coefficient = −47.64, p < 0.0001 and that QOL changes linearly over time with slopes ranging from 0.80 FI = 0.00 to −1.15 FI = 0.66 as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL.

ConclusionsFrailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.

KeywordsFrailty Quality of life Well-being Community-dwelling older people Electronic supplementary materialThe online version of this article doi:10.1007-s11136-015-1213-2 contains supplementary material, which is available to authorized users.

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Author: Gotaro Kojima - Steve Iliffe - Richard W. Morris - Yu Taniguchi - Denise Kendrick - Dawn A. Skelton - Tahir Masud - Ann 


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