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Tobacco Induced Diseases

, 14:22

First Online: 07 July 2016Received: 08 July 2015Accepted: 06 June 2016DOI: 10.1186-s12971-016-0086-7

Cite this article as: Farsalinos, K.E. & Baeyens, F. Tob. Induced Dis. 2016 14: 22. doi:10.1186-s12971-016-0086-7

Abstract

With this letter we express our concerns about the applicability of the proposed Margin of Exposure analysis as a method of risk assessment for propylene glycol and glycerol exposure from a shisha-pen type electronic cigarette. The studies used to determine the Margin of Exposure were evaluating the effects in humans or animals of continuous exposure to these chemicals in every single breath, whereas electronic cigarettes are used intermittently by consumers, resulting in lower and discontinuous exposure. Moreover, the authors make no clear distinction between irritation and harm, neither do they discuss the effects of exposure compared to continuous smoking.

KeywordsElectronic cigarettes Propylene glycol Glycerol Margin of exposure This comment refers to the article available at: http:-dx.doi.org-10.1186-s12971-015-0038-7.

This comment refers to the article available at: http:-dx.doi.org-10.1186-s12971-015-0038-7.

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Autor: Konstantinos E. Farsalinos - Frank Baeyens

Fuente: https://link.springer.com/







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