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Biological Procedures Online

, Volume 3, Issue 1, pp 43–53

Received: 19 May 2001Accepted: 30 October 2001DOI: 10.1251-bpo22

Cite this article as: Ren, J. & Wold, L.E. Biol Proced Online 2001 3: 43. doi:10.1251-bpo22

Abstract

Isolated adult cardiac ventricular myocytes have been a useful model for cardiovascular research for more than 20 years. With the recent advances in cellular physiology and transgenic techniques, direct measurement of isolated ventricular myocyte mechanics is becoming an increasingly important technique in cardiac physiology that provides fundamental information on excitation-contraction coupling of the heart, either in drug intervention or pathological states. The goal of this article is to describe the isolation of ventricular myocytes from both rats and mice, and the use of real-time beat-to-beat simultaneous recording of both myocyte contraction and intracellular Ca transients.

Indexing termsmyocyte contractility intracellular Ca transients edge detection Published: December 11, 2001

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Autor: Jun Ren - Loren E. Wold

Fuente: https://link.springer.com/







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