Impact of patient characteristics on the risk of influenza-ILI-related complicationsReport as inadecuate

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BMC Health Services Research

, 1:8

First Online: 21 August 2001Received: 11 June 2001Accepted: 21 August 2001DOI: 10.1186-1472-6963-1-8

Cite this article as: Irwin, D.E., Weatherby, L.B., Huang, WY. et al. BMC Health Serv Res 2001 1: 8. doi:10.1186-1472-6963-1-8


BackgroundWe sought to quantify the impact of patient characteristics on complications and health care costs associated with influenza and influenza-like illness ILI in a nonelderly population.

MethodsPatients with medical reimbursement claims for influenza in the 1996–1997 season were identified from the automated database of a large private New England Insurer NEI. Influenza care during the 21- day follow-up period was characterized according to age, gender, vaccine status, co-morbidities, prior influenza-ILI episodes, treatments, and recent health care costs and related diagnoses.

ResultsThere were 6,241 patients. Approximately 20% had preexisting chronic lung disease. Overall, 23% had health care services for possible complications, among which respiratory diagnoses were the most common 13%. Two percent of the influenza-ILI episodes involved hospitalization, with a median stay of five days. Factors most strongly predictive of hospitalizations and complications were preexisting malignancy hospitalizations OR = 3.7 and complications OR = 2.4, chronic heart disease OR = 3.2 and OR = 1.8, diabetes OR = 2.2 and OR = 1.7 and recent illnesses that would have counted as complications had they occurred during an influenza-ILI episode hospitalizations OR = 3.2 and complications OR = 1.5. The same factors affected influenza-related costs and total costs of care as dramatically as they affected complication rates.

ConclusionsInfluenza-ILI-related costs are driven by the characteristics that predict complications of influenza. Patients with chronic illness and those with recent acute respiratory events are the most likely to experience complications and hospitalizations.

Electronic supplementary materialThe online version of this article doi:10.1186-1472-6963-1-8 contains supplementary material, which is available to authorized users.

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Author: Debra E Irwin - Lisa B Weatherby - Wen-Yi Huang - Daniel M Rosenberg - Suzanne F Cook - Alexander M Walker


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