The Effect of Phacoemulsification Surgery on Corneal EndotheliumReportar como inadecuado




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Journal: Journal of Cells

Abstract: Introduction: Around half of world blindness and fifth of visual impairment are caused by cataract. Treatment of cataract and refractive errors correction improve 73.6% of blindness. Preservation of the Anterior chamber and corneal endothelium are very important aims during cataract surgery. Methodology: This prospective, observational study was done at King Fahd Hospital of the University KFUH, Alkhobar, Saudi Arabia. After getting the Institutional Review Board IRB approval, the study was initiated at KFUH between April 2016 and August 2016. After getting the patients- informed consents, a thorough assessment was done to each patient prior to surgery. All eyes enrolled in the study have undergone phacoemulsification surgery procedure. For each patient, one month after the phacoemulsification surgery , specular microscopy was performed. The phacodynamic parameters and surgery time were compared with the degree of endothelial cells loss, hexagonality and central corneal thickness. Results: The phacodynamic parameters used during phacoemulsification, namely, power AVG %, ultrasound time, and elliptical motion showed a strong correlation with the change of endothelial cell density all P< .001. The length of surgery also showed a positive correlation with the amount of endothelial cell loss P < .001. All of these parameters did not significantly affect corneal endothelial hexagonality except elliptical motion. Change in central corneal thickness was very minimal. Conclusion: Endothelial loss was significantly associated with phacoemulsification power, ultrasound time, elliptical motion and length of surgery. This study is one of very few studies which have investigated the effect of phacoemulsification cataract surgery on density and shape of corneal endothelial cells.

Medical Sciences

Journal of Cells

Month: 06-2017 Issue: 1







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