Design and implementation of a high yield production system for recombinant expression of peptidesReportar como inadecuado




Design and implementation of a high yield production system for recombinant expression of peptides - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Resumen

Making peptide pharmaceuticals involves challenging processes where many barriers, which include production and manufacture, need to be overcome. A non common but interesting research area is related to peptides with intracellular targets, which opens up new possibilities, allowing the modulation of processes occurring within the cell or interference with signaling pathways. However, if the bioactive sequence requires fusion to a carrier peptide to allow access into the cell, the resulting peptide could be such a length that traditional production could be difficult. The goal of the present study was the development of a flexible recombinant expression and purification system for peptides, as a contribution to the discovery and development of these potentially new drugs.Nota general

Articulo de publicacion SCOPUS



Autor: Rodríguez, Vida; - Asenjo de Leuze, Juan; - Andrews Farrow, Bárbara; -

Fuente: http://repositorio.uchile.cl/



DESCARGAR PDF




Documentos relacionados