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Theoretical Biology and Medical Modelling

, 9:3

First Online: 02 February 2012Received: 19 December 2011Accepted: 02 February 2012DOI: 10.1186-1742-4682-9-3

Cite this article as: Gong, Z. & Gong, Z. Theor Biol Med Model 2012 9: 3. doi:10.1186-1742-4682-9-3

Abstract

BackgroundGenerally, utility based decision making models focus on experimental outcomes. In this paper we propose a utility model based on molecular diffusion to simulate the choice behavior of Drosophila larvae exposed to different light conditions.

MethodsIn this paper, light-dark choice-based Drosophila larval phototaxis is analyzed with our molecular diffusion based model. An ISCEM algorithm is developed to estimate the model parameters.

ResultsBy applying this behavioral utility model to light intensity and phototaxis data, we show that this model fits the experimental data very well.

ConclusionsOur model provides new insights into decision making mechanisms in general. From an engineering viewpoint, we propose that the model could be applied to a wider range of decision making practices.

KeywordsDrosophila larva Phototaxis Decision making Utility Electronic supplementary materialThe online version of this article doi:10.1186-1742-4682-9-3 contains supplementary material, which is available to authorized users.

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Autor: Zhejun Gong - Zhefeng Gong

Fuente: https://link.springer.com/







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