Esophageal cancer treated by endoscopic submucosal dissection after neoadjuvant chemoradiotherapy: a case reportReport as inadecuate

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Journal of Medical Case Reports

, 8:439

First Online: 18 December 2014Received: 10 October 2014Accepted: 26 October 2014DOI: 10.1186-1752-1947-8-439

Cite this article as: Lim, J.H., Lee, S.A., Kang, G.E. et al. J Med Case Reports 2014 8: 439. doi:10.1186-1752-1947-8-439


IntroductionThe treatment of esophageal cancer remains clinically challenging because of the overall poor prognosis associated with the disease. The mortality rate associated with surgical treatment is high, and the majority of diagnosed patients are old. As such, surgery is not possible in many cases, even when the cancer has progressed to a resectable state.

Case presentationWe present the case of an 82-year-old Korean man who presented to our institution with intermittent odynophagia. Esophageal cancer with submucosal invasion and metastasis to three regional lymph nodes was diagnosed. After neoadjuvant chemoradiotherapy, his regional lymph nodes disappeared. Because of his poor pulmonary function, surgical treatment could not be performed. Endoscopic submucosal dissection was carried out instead, and endoscopic triamcinolone injections were performed serially. Neither recurrence nor abnormal symptoms such as dysphagia or regurgitation have developed for 36 months.

ConclusionsThe literature suggests that endoscopic submucosal dissection after chemoradiotherapy is a viable treatment modality in patients with esophageal cancer with a high surgical treatment risk.

KeywordsEndoscopic submucosal dissection Esophageal cancer Neoadjuvant chemoradiotherapy Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-8-439 contains supplementary material, which is available to authorized users.

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Author: Jang Hwan Lim - Sang Ah Lee - Gyoun Eun Kang - Jong Min Kim - Jin Kyung Park - Yun Jin Chung - Jae Kwon Jung - Chang



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