Future perspectives in melanoma research. Meeting report from the -Melanoma Bridge. Napoli, December 2nd-4th 2012Reportar como inadecuado




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Journal of Translational Medicine

, 11:137

First Online: 03 June 2013Received: 16 May 2013Accepted: 19 May 2013DOI: 10.1186-1479-5876-11-137

Cite this article as: Ascierto, P.A., Grimaldi, A.M., Acquavella, N. et al. J Transl Med 2013 11: 137. doi:10.1186-1479-5876-11-137

Abstract

Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third -Melanoma Research: -A bridge from Naples to the World- meeting, shortened as -Bridge Melanoma Meeting- took place in Naples, December 2 to 4, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients.

Electronic supplementary materialThe online version of this article doi:10.1186-1479-5876-11-137 contains supplementary material, which is available to authorized users.

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Autor: Paolo A Ascierto - Antonio M Grimaldi - Nicolas Acquavella - Lorenzo Borgognoni - Luana Calabrò - Natale Cascinelli - Ale

Fuente: https://link.springer.com/







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