Stiff limb syndrome: a case reportReport as inadecuate

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Cases Journal

, 3:60

First Online: 12 February 2010Received: 30 November 2009Accepted: 12 February 2010DOI: 10.1186-1757-1626-3-60

Cite this article as: Hajjioui, A., Benbouazza, K., Faris, M.E.A. et al. Cases Journal 2010 3: 60. doi:10.1186-1757-1626-3-60


IntroductionStiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature.

Case presentationA 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg-day and baclofen 30 mg-day.

ConclusionThis clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography

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Author: Abderrazak Hajjioui - Karima Benbouazza - Mohamed El Alaoui Faris - Amina Missaoui - Najia Hajjaj Hassouni


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