Multiple tuberculous nodules with metachronous changes: a case reportReportar como inadecuado

Multiple tuberculous nodules with metachronous changes: a case report - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Research Notes

, 6:320

First Online: 12 August 2013Received: 23 April 2013Accepted: 08 August 2013DOI: 10.1186-1756-0500-6-320

Cite this article as: Fukusumi, M., Ibe, T., Takeoka, S. et al. BMC Res Notes 2013 6: 320. doi:10.1186-1756-0500-6-320


BackgroundSpontaneous regression of lesions occurs in non-infectious benign diseases, such as sarcoidosis, as well as in infectious diseases, such as tuberculosis. Lung cancer and malignant lymphoma, on the other hand, rarely follow a similar course. We report a rare case of lung tuberculosis that presented with multiple nodules with metachronous changes in size.

Case presentationWe describe the case of a 50-year-old immunocompetent Japanese man with pulmonary tuberculosis in the form of multifocal nodules. He came to our hospital because of a chest X-ray abnormality. During the course of observation, some nodules reduced while others enlarged in size. Two years after the first visit, fever and pleural effusion appeared. The sputum examination turned out to be positive for tuberculosis. A course of anti-tubercular agents resolved the pleural effusion and multifocal nodules.

ConclusionDifferences in the manner of granuloma formation suggest that the local immune response can be different even in the same lung field.

KeywordsPulmonary tuberculosis Multifocal nodules Spontaneous regression Electronic supplementary materialThe online version of this article doi:10.1186-1756-0500-6-320 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Munehisa Fukusumi - Tatsuya Ibe - Shinjiro Takeoka - Kazushige Wakuda - Atsuto Mouri - Yoichiro Hamamoto - Mitsuhiro Kamimu


Documentos relacionados