Quality of life in patients with gastric cancer: translation and psychometric evaluation of the Iranian version of EORTC QLQ-STO22Reportar como inadecuado

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BMC Cancer

, 9:305

First Online: 28 August 2009Received: 27 April 2009Accepted: 28 August 2009DOI: 10.1186-1471-2407-9-305

Cite this article as: Sadighi, S., Montazeri, A., Sedighi, Z. et al. BMC Cancer 2009 9: 305. doi:10.1186-1471-2407-9-305


BackgroundDisease and treatment related events, can adversely affect the quality of life of patients with cancer. The purpose of this study was to translate and validate a gastric cancer specific health related quality of life questionnaire EORTC QLQ-STO22 for Iranian patients suffering from gastric cancer.

MethodsForward-backward procedure was applied to translate the English language version of the EORTC QLQ-STO22 into Persian Iranian language. Then, the questionnaire and the EORTC core quality of life instrument QLQ-C30 were administered to a sample of patients with confirmed diagnosis of gastric cancer. All patients filled in questionnaires before and after one month of treatment. Patients were divided into two groups based on intension of treatment curative vs. palliative. Reliability and validity of the module was tested by internal consistency and known group comparisons, respectively.

ResultsIn all, 105 patients were entered into the study. Cronbach-s alpha for multi-item scales to test reliability ranged from 0.54 to 0.87. The questionnaire discriminated well between clinically distinct subgroups of patients both before and after treatment lending support to its convergent and clinical validity.

ConclusionOverall, the Iranian version of the EORTC QLQ-STO22 demonstrated a good reliability and clinical validity to support its use in combination with core questionnaire in outcome studies of gastric cancer in Iran. However, using the QLQ-STO22 in a wide range of Iranian patients with gastric cancer should allow further confirmation for its psychometric properties.

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Autor: Sanamber Sadighi - Ali Montazeri - Zahra Sedighi - Mohammad Ali Mohagheghi - Hossein Froutan

Fuente: https://link.springer.com/

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