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BMC Cardiovascular Disorders

, 9:43

First Online: 28 August 2009Received: 05 June 2009Accepted: 28 August 2009DOI: 10.1186-1471-2261-9-43

Cite this article as: Vaartjes, I., de Borst, G., Reitsma, J. et al. BMC Cardiovasc Disord 2009 9: 43. doi:10.1186-1471-2261-9-43


BackgroundAs the population ages, peripheral arterial disease PAD in the lower extremities will become a larger public health problem. Awareness in patients as well clinicians of the high risk of morbidity and mortality is important but seems currently low. Insights in absolute mortality risks following admission for PAD in the lower extremities can be useful to improve awareness as they are easy to interpret.

MethodsA nationwide cohort of 4,158 patients with an initial admission for PAD in the lower extremities was identified through linkage of the national hospital and population register in 1997 and 2000.

ResultsOver 60% of 4,158 patients were men. 28 days, 1 year and 5 year mortality risk were 2.4%, 10.3% and 31.0% for men and 3.5%, 10.4% and 27.4% for women. Coronary heart disease and stroke were frequent cause of death. Five years mortality risk was higher for men compared to women HR 1.36, 95% CI 1.21–1.53.

ConclusionIn conclusion, our findings demonstrate that, 5 year mortality risk is high, especially in men and comparable to that of patients admitted for acute myocardial infarction or ischemic stroke. Though, in general population the awareness of the severity of PAD in the lower extremities is significantly lower than that for any other cardiovascular disease and it seems that cardiovascular risk factor management for prevention in PAD patients is very modest.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2261-9-43 contains supplementary material, which is available to authorized users.

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Autor: I Vaartjes - GJ de Borst - JB Reitsma - A de Bruin - FL Moll - DE Grobbee - ML Bots

Fuente: https://link.springer.com/

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