Comparison of the prognosis and recurrence of apparent early-stage ovarian tumors treated with laparoscopy and laparotomy: a meta-analysis of clinical studiesReportar como inadecuado




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BMC Cancer

, 15:597

First Online: 26 August 2015Received: 24 December 2014Accepted: 14 August 2015DOI: 10.1186-s12885-015-1604-3

Cite this article as: Zhang, Y., Fan, S., Xiang, Y. et al. BMC Cancer 2015 15: 597. doi:10.1186-s12885-015-1604-3

Abstract

BackgroundThis meta-analysis aimed to evaluate the prognosis and recurrence of apparent early-stage ovarian tumors treated with laparoscopy compared with laparotomy.

MethodsClinical studies published in English were retrieved from the computerized databases Medline and Embase. A meta-analysis was performed to investigate the differences in the efficacy and safety of laparoscopy versus laparotomy in terms of postoperative complications, lengths of hospital stay, recurrence rates, and disease-free survival times using the random effects model. The studies were independently reviewed by two investigators. Data from the eligible studies were extracted, and the meta-analysis was performed using the Comprehensive Meta-Analysis program, version 2 CMA-2; Biostat, Englewood, NJ, USA.

ResultsA total of 8 studies were included in the analysis. The results showed that laparoscopic surgery was significantly associated with lower rates of complications OR = 0.433, P = 0.019 and shorter postoperative hospital stays weighted mean difference WMD = −0.974, P < 0.001. There was no significant difference in the rates of recurrence OR = 0.707, P = 0.521 between patients with apparent early-stage ovarian tumors who were treated using laparoscopy and those who underwent laparotomy. No publication bias was detected.

ConclusionsLaparoscopic surgery shows favorable prognostic outcomes in terms of postoperative complication rates and postoperative hospital stay durations. Further studies with longer follow-up periods are required to confirm recurrence and survival outcomes after laparoscopic surgery in patients with apparent early-stage ovarian tumors.

AbbreviationsFIGOthe International Federation of Gynecology and Obstetrics

CMA-2Comprehensive Meta-Analysis Program, version 2

Ying Zhang and Shuying Fan contributed equally to this work.

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Autor: Ying Zhang - Shuying Fan - Yang Xiang - Hua Duan - Li Sun

Fuente: https://link.springer.com/







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