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Journal of Medical Case Reports

, 3:8331

First Online: 16 July 2009Received: 03 October 2008Accepted: 09 February 2009DOI: 10.4076-1752-1947-3-8331

Cite this article as: Ferrari, A.B., Pulcini, G., Gheza, F. et al. J Med Case Reports 2009 3: 8331. doi:10.4076-1752-1947-3-8331


IntroductionBreast cancer is the most frequent type of tumor and the second leading cause of death in women. Metastases are present in nearly 60% of cases at the time of diagnosis with the lymph nodes, skeleton, lungs, brain and liver as the most frequent sites of metastases. Gastrointestinal involvement is rare, present in only 10% of all the cases. There is a very low risk of developing breast cancer in men.

Case presentationA 68-year-old man, with a past history of ductal breast cancer, presented with duodenal obstruction. Medical treatment was attempted without success, so he underwent surgery with subtotal gastrectomy and resection of the first portion of the duodenum. Histological examination showed a duodenal metastasis originating from the previous carcinoma of the breast. Five months after surgery, the patient is alive and well.

ConclusionGastrointestinal metastases should be considered in patients with a past history of breast cancer. Surgical treatment should be performed in patients who are symptomatic and in good general condition. To our knowledge this is the only case of a gastrointestinal metastasis from breast carcinoma in a man.

AbbreviationsCEACarcinoembryonic antigen


CTComputer Tomography

CDX2Caudal Type Homeobox Transcription Factor 2

EREstrogen Receptors

GCDFP-15Gross Cystic Disease Fluid Protein 15


HER2Human Epidermal Growth Factor Receptor 2

PPIProton Pump Inhibitors.

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Fuente: https://link.springer.com/

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