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Cell Regeneration

, 3:5

First Online: 29 March 2014Received: 28 January 2014Accepted: 11 March 2014DOI: 10.1186-2045-9769-3-5

Cite this article as: Prigione, A. & Adjaye, J. Cell Regen 2014 3: 5. doi:10.1186-2045-9769-3-5

Abstract

Genomic aberrations induced by somatic cell reprogramming are a major drawback for future applications of this technology in regenerative medicine. A new study by Ji et al. published in Stem Cell Reports suggests a counteracting strategy based on balancing the mitochondrial-oxidative stress pathway through antioxidant supplementation.

KeywordsAntioxidants Mitochondria Reprogramming iPSCs Genomic aberrations Electronic supplementary materialThe online version of this article doi:10.1186-2045-9769-3-5 contains supplementary material, which is available to authorized users.

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Author: Alessandro Prigione - James Adjaye

Source: https://link.springer.com/







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