A retrospective analysis of dengue fever case management and frequency of co-morbidities associated with deathsReportar como inadecuado

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BMC Research Notes

, 7:205

First Online: 01 April 2014Received: 26 July 2013Accepted: 28 March 2014DOI: 10.1186-1756-0500-7-205

Cite this article as: Saqib, M.A.N., Rafique, I., Bashir, S. et al. BMC Res Notes 2014 7: 205. doi:10.1186-1756-0500-7-205


BackgroundDengue epidemic in Lahore 2011 resulted in hundreds of deaths and affected thousands. As most of the studies were focused on its diagnosis and treatment, scanty data is available on associated diseases-co-morbidities in these patients that could have contributed to a higher mortality. There were no local guidelines available on recording, reporting and management of these co-morbidities. The objective of this study was to analyze the initial presentations of dengue cases and to estimate the frequency of co-morbidities in dengue patients.

MethodsData of 556 dengue cases was retrieved from 2 major public sector tertiary-care hospitals for patients who were admitted during 2011 epidemic and a case record analysis was done. Data was retrieved from patient’s information reports which included demography, signs and symptoms and the laboratory investigations. In addition verbal autopsy of deceased cases was also done from their relatives using standardized WHO verbal autopsy form after making modifications as per needed.

ResultsOf 556 cases studied, 390 70% were males. The mean age was 36 years and 30% of the cases were between 20-29 years. Average duration of the hospital stay was 6 days. Out of the total, 435 78% were dengue fever DF cases followed by dengue hemorrhagic fever DHF in 95 17% and dengue shock syndrome DSS in 26 4% cases. A total of 40 cases died and among them 17 were diagnosed with DSS, 13 DF and 10 DHF. Further the verbal autopsy from relatives of deceased cases showed 29 60% deceased had co-morbid diseases which included hypertension, diabetes etc. DSS was common in patients who had hypertension 27 either alone or associated with other illnesses.

ConclusionsCo-morbidities with dengue infection were seen in 60% deceased cases indicating the reasons for high dengue related complications and death.

KeywordsDengue Co-morbid Hypertension Electronic supplementary materialThe online version of this article doi:10.1186-1756-0500-7-205 contains supplementary material, which is available to authorized users.

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Autor: Muhammad Arif Nadeem Saqib - Ibrar Rafique - Saira Bashir - Arsalan Ahmad Salam

Fuente: https://link.springer.com/

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