Idiopathic pulmonary fibrosis in BRIC countries: the cases of Brazil, Russia, India, and ChinaReport as inadecuate




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BMC Medicine

, 13:237

First Online: 24 September 2015Received: 11 September 2015Accepted: 18 September 2015DOI: 10.1186-s12916-015-0495-0

Cite this article as: Richeldi, L., Rubin, A.S., Avdeev, S. et al. BMC Med 2015 13: 237. doi:10.1186-s12916-015-0495-0

Abstract

Idiopathic pulmonary fibrosis IPF, the prototype of interstitial lung diseases, has the worst prognosis and is the only interstitial lung disease for which approved pharmacological treatments are available. Despite being considered a rare disease, IPF patients pose major challenges to both physicians and healthcare systems. It is estimated that a large number of IPF patients reside in BRIC countries Brazil, Russia, India, and China given their overall total population of approximately 3 billion inhabitants. Nevertheless, the limited availability of chest imaging in BRIC countries is considered a chief obstacle to diagnosis, since high-resolution computed tomography of the chest is the key diagnostic test for IPF. Further, obtaining reliable lung function tests and providing treatment access is difficult in the more rural areas of these countries. However, IPF might represent an opportunity for BRIC countries: the exponentially increasing demand for the enrollment of IPF patients in clinical trials of new drugs is predicted to face a shortage of patients – BRIC countries may thus play a crucial role in advancing towards a cure for IPF.

KeywordsBRIC countries High-resolution computed tomography Idiopathic pulmonary fibrosis Nintedanib Pirfenidone  Download fulltext PDF



Author: Luca Richeldi - Adalberto Sperb Rubin - Sergey Avdeev - Zarir F. Udwadia - Zuo Jun Xu

Source: https://link.springer.com/







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