Kawasaki disease following Rocky Mountain spotted fever: a case reportReport as inadecuate

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Journal of Medical Case Reports

, 3:7320

First Online: 06 July 2009Received: 11 March 2008Accepted: 23 January 2009DOI: 10.4076-1752-1947-3-7320

Cite this article as: Bal, A.K. & Kairys, S.W. J Med Case Reports 2009 3: 7320. doi:10.4076-1752-1947-3-7320


IntroductionKawasaki disease is an idiopathic acute systemic vasculitis of childhood. Although it simulates the clinical features of many infectious diseases, an infectious etiology has not been established. This is the first reported case of Kawasaki disease following Rocky Mountain spotted fever.

Case presentationWe report the case of a 4-year-old girl who presented with fever and petechial rash. Serology confirmed Rocky Mountain spotted fever. While being treated with intravenous doxycycline, she developed swelling of her hands and feet. She had the clinical features of Kawasaki disease which resolved after therapy with intravenous immune globulin IVIG and aspirin.

ConclusionThis case report suggests that Kawasaki disease can occur concurrently or immediately after a rickettsial illness such as Rocky Mountain spotted fever, hypothesizing an antigen-driven immune response to a rickettsial antigen.

AbbreviationsELISAenzyme-linked immunosorbent assay

IFAimmunofluorescence antibody

IGIVimmune globulin intravenous

IgMImmunoglobulin M

IgGImmunoglobulin G

KDKawasaki disease

RMSFRocky Mountain spotted fever.

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Author: Aswine K Bal - Steven W Kairys

Source: https://link.springer.com/

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