Horizontal partial laryngectomy in mucoepidermoid carcinoma of the larynx after failure of laser surgery followed by radiotherapy: a case reportReport as inadecuate




Horizontal partial laryngectomy in mucoepidermoid carcinoma of the larynx after failure of laser surgery followed by radiotherapy: a case report - Download this document for free, or read online. Document in PDF available to download.

Cases Journal

, 2:8421

First Online: 02 July 2009Received: 07 March 2008Accepted: 09 February 2009DOI: 10.4076-1757-1626-2-8421

Cite this article as: Luna-Ortiz, K., Cano-Valdez, A.M., Chacón, A.P. et al. Cases Journal 2009 2: 8421. doi:10.4076-1757-1626-2-8421

Abstract

IntroductionTumors of the minor salivary glands in the larynx are rare and represent <1%. They usually appear between the 4 and 7 decades of life. The most common site of occurrence is the supraglottis; however, these neoplasms can appear at any location in the larynx. Pulmonary metastases are the most frequent site for distant disease.

Case presentationWe present the case of a 34-year-old Hispanic male with a history of cigarette smoking. He was admitted to our Institution in 2002 with a 1-year evolution of odynophagia, initially to solids and then to liquids. The patient was referred to our Institution for an undifferentiated carcinoma of the epiglottis treated one week earlier with laser surgery and positive surgical margins. Upon admittance, the patient did not demonstrate any tumor activity. A review of the slides confirmed undifferentiated carcinoma. Chemo-radiotherapy was proposed to the patient, but he accepted only radiotherapy and received a total dose of 70 Gy. The patient was followed-up every 3 months. Two years later, follow-up nasofibrolaryngoscopy demonstrated clear evidence of tumor activity at the site of the primary tumor supraglottis. No cervical adenopathies were found either clinically or radiologically. Biopsy of the lesion was inconclusive; hence, the patient was scheduled for a suspension microlaryngoscopy with transoperative study, performing afterwards a supraglottic horizontal laryngectomy. Histological diagnosis reported ulcerated, high-grade supraglottic mucoepidermoid carcinoma with lymphatic permeation and invasion to the striate muscle and adipose tissue. The borders and surgical bed were free of neoplasm. The patient evolved satisfactorily. At 4 years following treatment, the patient is disease free.

ConclusionRecurrence must be considered when planning treatment, and organ preservation surgery is justified, especially in young patients.

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Author: Kuauhyama Luna-Ortiz - Ana María Cano-Valdez - Adela Poitevin Chacón - Angel Herrera Gómez

Source: https://link.springer.com/







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