Chronic eosinophilic pneumonia: a case report and review of the literatureReport as inadecuate

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Cases Journal

, 2:7735

First Online: 02 July 2009Received: 09 April 2009Accepted: 11 June 2009DOI: 10.4076-1757-1626-2-7735

Cite this article as: Sano, S., Yamagami, K. & Yoshioka, K. Cases Journal 2009 2: 7735. doi:10.4076-1757-1626-2-7735


A 66-year-old female patient was admitted with a one year history of low-grade fever and shortness of breath with worsening symptoms. A computed tomography CT scan of the chest was performed, which revealed bilateral homogenous consolidation with subpleural predominance in the corresponding area. The percentage of eosinophils in the bronchoalveolar lavage BAL fluid was 98% and histological examination showed remarkable accumulation of eosinophils and lymphocytes in the alveoli and interstitium, with mild interstitial fibrosis. The diagnosis of idiopathic chronic eosinophilic pneumonia was confirmed. Intravenous methylprednisolone pulse therapy 500 mg daily for three days followed by 30 mg of oral prednisolone showed dramatic response. She was essentially normal after one year follow up.

CEP is characterized by chronic and progressive clinical features and specific pathological findings. We review the epidemiology, clinical, diagnosis, and therapy of the CEP.

AbbreviationsBALbronchoalveolar lavage

CEPchronic eosinophilic pneumonia.

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Author: Soichi Sano - Keiko Yamagami - Katsunobu Yoshioka


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