Morgellons disease, illuminating an undefined illness: a case seriesReport as inadecuate

Morgellons disease, illuminating an undefined illness: a case series - Download this document for free, or read online. Document in PDF available to download.

Journal of Medical Case Reports

, 3:8243

First Online: 01 July 2009Received: 28 November 2008Accepted: 17 March 2009DOI: 10.4076-1752-1947-3-8243

Cite this article as: Harvey, W.T., Bransfield, R.C., Mercer, D.E. et al. J Med Case Reports 2009 3: 8243. doi:10.4076-1752-1947-3-8243


IntroductionThis review of 25 consecutive patients with Morgellons disease MD was undertaken for two primary and extremely fundamental reasons. For semantic accuracy, there is only one -proven- MD patient: the child first given that label. The remainder of inclusive individuals adopted the label based on related descriptions from 1544 through 1884, an internet description quoted from Sir Thomas Browne 1674, or was given the label by practitioners using similar sources. Until now, there has been no formal characterization of MD from detailed examination of all body systems. Our second purpose was to differentiate MD from Delusions of Parasitosis DP, another -informal- label that fit most of our MD patients. How we defined and how we treated these patients depended literally on factual data that would determine outcome. How they were labeled in one sense was irrelevant, except for the confusing conflict rampant in the medical community, possibly significantly skewing treatment outcomes.

Case presentationClinical information was collected from 25 of 30 consecutive self-defined patients with Morgellons disease consisting of laboratory data, medical history and physical examination findings. Abnormalities were quantified and grouped by system, then compared and summarized, but the numbers were too small for more complex mathematical analysis. The quantification of physical and laboratory abnormalities allowed at least the creation of a practical clinical boundary, separating probable Morgellons from non-Morgellons patients. All the 25 patients studied meet the most commonly used DP definitions.

ConclusionsThese data suggest Morgellons disease can be characterized as a physical human illness with an often-related delusional component in adults. All medical histories support that behavioral aberrancies onset only after physical symptoms. The identified abnormalities include both immune deficiency and chronic inflammatory markers that correlate strongly with immune cytokine excess. The review of 251 current NLM DP references leads us to the possibility that Morgellons disease and DP are grossly truncated labels of the same illness but with the reversal of the cause-effect order. Further, the patients- data suggest that both illnesses have an infectious origin.

Download fulltext PDF

Author: William T Harvey - Robert C Bransfield - Dana E Mercer - Andrew J Wright - Rebecca M Ricchi - Mary M Leitao


Related documents