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Cases Journal

, 2:6157

First Online: 01 July 2009Received: 23 February 2009Accepted: 25 May 2009DOI: 10.4076-1757-1626-2-6157

Cite this article as: Papaliagkas, V.T., Tsolaki, M.N., Kimiskidis, V.K. et al. Cases Journal 2009 2: 6157. doi:10.4076-1757-1626-2-6157

Abstract

We present a case of a 74-year-old Greek male who suffered from paraphasias, memory and orientation problems. The patient was assessed with neuropsychometric tests, auditory event-related potentials and cerebrospinal fluid proteins and was diagnosed with mild cognitive impairment. The emphasis on the case is on the unexplained high levels of P300 and Slow wave of the auditory event-related potentials.

P300 is believed to be delayed in Alzheimer-s Disease AD, however in our case it was extremely prolonged in baseline and follow-up examinations without AD being diagnosed. This might suggest that AD is a complex and multifactorial disease.

AbbreviationsADAlzheimer-s disease

CDRClinical Dementia Rating

CSFCerebrospinal fluid

ERPEvent-related potentials

MCIMild cognitive impairment

MMSEMini-Mental State Examination

MRIMagnetic Resonance Imaging

SWSlow wave.

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Autor: Vasileios T Papaliagkas - Magda N Tsolaki - Vasileios K Kimiskidis - Georgios Anogianakis

Fuente: https://link.springer.com/



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