Nutritional optic and peripheral neuropathy: a case reportReport as inadecuate

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Cases Journal

, 2:7762

First Online: 05 June 2009Received: 01 August 2008Accepted: 16 March 2009DOI: 10.4076-1757-1626-2-7762

Cite this article as: Nightingale, L.M. & Paviour, D.C. Cases Journal 2009 2: 7762. doi:10.4076-1757-1626-2-7762


IntroductionThe link between nutritional status and either optic or peripheral neuropathies is well established with tobacco, ethanol, deficiencies in thiamine, vitamin A, B12, B3 and B6 and protein-energy malnutrition all being causative.

Case presentationWe describe the case of a 32-year-old Afro-Caribbean of Jamaican origin presenting with blurred vision and a painful burning sensation in his feet. The clinical features were consistent with optic and peripheral neuropathy.

ConclusionsThe patient followed a strict vegan diet and consumed no animal products. A review of the literature highlights similarities between this case and Strachan-s syndrome, a combination of optic and peripheral neuropathy and cutaneous excoriation, providing further evidence for the association between this clinical presentation, dietary deficiency and, as recently postulated, previous residence in a tropical or sub-tropical climate.

List of abbreviationsACEAngiotensin-Converting Enzyme

APTTactivated partial thromboplastin time

BMIBasal metabolic index

CRPC-reactive protein


ENAExtractable nuclear antigens

ESRErythrocyte sedimentation rate

LHONLeber-s hereditary optic neuropathy.

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Author: Laura M Nightingale - Dominic C Paviour


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